Evaluating Vectors for Gene Therapy

Hu-M™ mice can be used to analyze the in vivo expression patterns and hemotoxicity of gene therapy vectors.  Gene therapies targeting CD34+ stem cells ex-vivo can then be used to construct Hu-M™ mice. Hu-M™ mice generated with altered CD34+ cells allows for a rapid analysis to determine targeting of gene therapy vectors in human lymphocyte lineages and potential adverse effects on hematopoiesis. HuMurine personnel have an extensive background involving testing of lentiviral vector transduction of CD34+ cells and generation of humanized mice with transduced cells

Customizable studies available! For pricing and availability please contact us at info@humurine.com or call 909-859-1050.