PDX/Hu-MTM Based Contract Services

The PDX/Hu-M™ Mice are implanted with HLA matched human patient derived xenograft (PDX) tumors for evaluating the efficacy, pharmacokinetic profile, and immune related adverse events of immune-checkpoint modulators. HuMurine’s validation matrix is specifically focused on quantifying the anti-tumor T cells response in PDX/ Hu-M™ Mice using complex flow cytometric analysis including tetramer staining.